张晨

发布时间:2023-05-08浏览次数:917



个人简介

张晨,女,全讯白菜网,副教授,生物医学工程专业

教育经历

2007.9-2011.6   山东农业大学   动植物检疫专业   本科

2011.9-2013.6   吉林大学   生物医学工程专业   硕士(硕博连读)

2013.9-2016.12   吉林大学   再生医学专业   博士

2015.02-2016.10   日本理化学研究所  再生医学专业 国际博士联合培养

主要参与的项目

1国家级

黏附性胰岛素样生长因子-1的Sortase A酶法制备以及其对医用金属钛材料表面修饰的应用

81801849

主持
2省部级

贻贝粘附序列修饰的VEGF用于制备活性医用钛材料及其功能研究

2020J05176

主持
3横向

三维打印技术制备活性因子修饰的骨修复材料及应用


主持
4横向

基于3D打印技术的多相活性生物支架的制备


主持
5校级

海参多糖类成分预防基于循环肿瘤细胞诱导的肿瘤术后再转移机理研究


主持





主要成果

论文

1.human colorectal cancer stem cells. Biochem Biophys Res Commun, 2021. 534: p. 254-260.

2.Li, G., et al., Inhibitory Effects of Sulfated Polysaccharides from the Sea Cucumber Cucumaria Frondosa against Abeta40 Aggregation and Cytotoxicity. ACS Chem Neurosci, 2021. 12(11): p. 1854-1859.

3.Fu, C., et al., Therapeutic Antitumor Efficacy of Cancer Stem Cell-Derived DRibble Vaccine on Colorectal Carcinoma. Int J Med Sci, 2021. 18(14): p. 3249-3260.

4.Zhong, C., et al., Achyranthes bidentata polysaccharide can safely prevent NSCLC metastasis via targeting EGFR and EMT. Signal Transduct Target Ther, 2020. 5(1): p. 178.

5.Zhai, S., et al., A novel UPLC/MS/MS method for rapid determination of murrayone in rat plasma and its pharmacokinetics. J Pharm Biomed Anal, 2020. 180: p. 113046.

6.Li, Y., et al., WDR74 modulates melanoma tumorigenesis and metastasis through the RPL5-MDM2-p53 pathway. Oncogene, 2020.

7.Li, Y., et al., WDR74 induces nuclear beta-catenin accumulation and activates Wnt-responsive genes to promote lung cancer growth and metastasis. Cancer Lett, 2020. 471: p. 103-115.

8.Zhang, C., et al., Functionalized MoS2-erlotinib produces hyperthermia under NIR. J Nanobiotechnology, 2019. 17(1): p. 76.

9.Zhai, S., et al., A novel UPLC/MS/MS method for rapid determination of murrayone in rat plasma and its pharmacokinetics. J Pharm Biomed Anal, 2019. 180: p. 113046.

10.Xie, R., et al., Mitochondria and Nuclei Dual-Targeted Hollow Carbon Nanospheres for Cancer Chemophotodynamic Synergistic Therapy. Mol Pharm, 2019. 16(5): p. 2235-2248.

11.Lu, Y., et al., Circulation patterns and seed-soil compatibility factors cooperate to cause cancer organ-specific metastasis. Exp Cell Res, 2019. 375(1): p. 62-72.

12.Li, Y., et al., WDR74 induces nuclear beta-catenin accumulation and activates Wnt-responsive genes to promote lung cancer growth and metastasis. Cancer Lett, 2019.

13.Fu, C., et al., Enhanced anticancer effect of oncostatin M combined with salinomycin in CD133(+) HepG2 liver cancer cells. Oncol Lett, 2019. 17(2): p. 1798-1806.

14.Dharmatti, R., et al., Escherichia coli expression, purification, and refolding of human folate receptor alpha (hFRalpha) and beta (hFRbeta). Protein Expr Purif, 2018. 149: p. 17-22.

15.Zhang, C., et al., Thioridazine elicits potent antitumor effects in colorectal cancer stem cells. Oncol Rep, 2017. 37(2): p. 1168-1174.

16.Zhang, C., et al., Grape seed proanthocyanidins induce mitochondrial pathway-mediated apoptosis in human colorectal carcinoma cells. Oncol Lett, 2017. 14(5): p. 5853-5860.

17.Wang, H.Y., et al., Hepatocyte growth factor inhibits tubular epithelialmyofibroblast transdifferentiation by suppression of angiotensin II via the JAK2/STAT3 signaling pathway. Mol Med Rep, 2017. 15(5): p. 2737-2743.

18.Zhang, C., et al., A Bioorthogonal Approach for the Preparation of a Titanium-Binding Insulin-like Growth-Factor-1 Derivative by Using Tyrosinase. Angew Chem Int Ed Engl, 2016. 55(38): p. 11447-51.

19.Zhang, C., et al., Salinomycin inhibits the growth of colorectal carcinoma by targeting tumor stem cells. Oncol Rep, 2015. 34(5): p. 2469-76.

20.Fu, C., et al., Isolation, identification and differentiation of human embryonic cartilage stem cells. Cell Biol Int, 2015. 39(7): p. 777-87.

专利

序号

专利名称

类型

申请或授权号

1

《一种高活性胰岛素样生长因子-1的制备方法》

发明

201810304677.2

2

《一种用于动物细胞培养的自动清洁水浴锅》

实用新型

ZL201520232890.9

3

《一种重组刺参胶原多肽、制备方法及其应用》

发明

201910279919.1

4

《一种海参样品存放箱》

实用新型

201920679527X

5

《一种实验用海参研磨机》

实用新型

201920680167.5

6

《一种海参膜透析磁力搅拌装置》

实用新型

201920680577.X

7

《一种海参内脏清洗装置》

实用新型

201921114728.1

8

《一种海洋养殖饵料投喂装置》

实用新型

201920968427.9