黄扬杰

发布时间:2023-05-08浏览次数:1305



个人简介

黄扬杰、男、副教授福建省高层次人才(C类),2021年获福建省“闽江学者特聘教授”称号。主要从事研究方向:有机氟化学,高效氟化试剂的设计与合成,高附加值含氟精细化学品的开发等。

教育经历

2008-2012  广西大学 本科

2012-2017 福州大学博士导师: 翁志强教授

2017-2020 加州大学旧金山分校博士后合作导师: Prof. Michael Evans

主要参与的项目

7. 企业委托项目(新型松材线虫防治药剂——氟吡菌酰胺的绿色合成),2023.12-2024.12。(排名第二)

6. 福建省科技厅高校产学合作项目(高纯氢氟醚的产业化关键技术研究),2023.01-2025.12。(排名第二)

5. 福建省自然基金面上项目(多氟腈前驱体的合成及其反应活性研究),2022.08-2025.08。(主持)

4. 国家自然基金青年项目(基于[18F]SCF3标记构建靶向血管紧张素转化酶2的PET分子探针的研究),2023.01-2025.12。(主持)

3.国家基金面上项目(配体修饰异核双金属全氟烷基配合物的合成及反应性质研究),2021.01-2024.12。(排名第二)

2.重点实验室开放课题(含氟电解质及添加剂的合成与性能研究)2021年-2023年。(主持)

1.国家基金面上项目(高活性三氟甲硫基亲核试剂的研制与应用)2018.01-2021.12。(排名第二)


主要成果

20.  Zirconium-CatalyzedSynthesisof6‑(Trifluoromethyl)‑2H‑pyran-2- ones via C−C Bond Cleavage. Zipeng Zhang#, Yangjie Huang#, Zihang Yuan, Jianrong Xia,* Zhiqiang Weng*. 2024, Doi.org/10.1021/acs.joc.4c00227.

19.  One–Pot Assembly of 2-Trifluoromethyl Benzothiazole and Benzoselenazole via Copper–Mediated Three–Component Cascade Reaction. Yangjie Huang, Chenhui You, Biqiong Hong, Xiaoyan Han*, Zhiqiang Weng*. 2024, Doi.org/10.1002/asia.202400331.

18. 2,2,2-Trifluoroacetaldehyde O‑(Aryl)oxime: A Precursor of Trifluoroacetonitrile. Bo Lin, Yunfei Yao, Yangjie Huang*, and Zhiqiang Weng*. Org. Lett., 2022, 24, 2055−2058.

17.  Copper-mediated three-component synthesis of 2-trifluoromethyl benzimidazoles. Chenhui You, Yangjie Huang*, Yi You, Zhiqiang Weng     *. Org. Chem. Front., 2022, 9, 3247–3254.

16.  Synthesis of 2,3-Bis(trifluoromethylseleno) Indoles through an Oxidative Copper-Mediated Domino Reaction. Hui Wang, Yunfei Yao, Zipeng Zhang, Yangjie Huang*, Zhiqiang Weng*. J. Org. Chem., 2022, 87, 3605−3612.

15.  Regioselective synthesis of 3-trifluoromethyl 1,2,4-triazoles via  photocycloaddition of sydnone with CF3CN. Bo Lin, Yunfei Yao, Yangjie Huang*, Qi Lin, Zhiqiang Weng*. Chem. Commun., 2022, 58, 12224-12227.

14.  Synthesis of 2-trifluoromethyl thiazoles via [3 + 2] cycloaddition of pyridinium 1,4-zwitterionic thiolates with CF3CN. Yunfei Yao, Bo Lin, Minze Wu, Yafang Zhang, Yangjie Huang*, Xiaoyan Han*, and Zhiqiang Weng*. Org. Biomol. Chem., 2022, 20, 8761-8765.

13.  An aerobic copper-mediated domino process for the synthesis of 3-(trifluoromethylseleno)indoles. Hui Wang, Yunfei Yao, Yi You*, Yangjie Huang and Zhiqiang Weng*. Org. Biomol. Chem., 2022, 20, 2115–2120.

12.  [(bpy)CuSCF3]: A Practical and Efficient Reagent for the Construction of C–SCF3 Bonds. Yangjie Huang, Mengjia Zhang, Qi Lin*, Zhiqiang Weng*. Synlett, 2021, 32, 109–118.

Before MJU

11.  Huang Y, Zhao N, Wang YH, Truillet C, Wei J, Parker MFL, Blecha JE, Drake CR, VanBrocklin HF, Ruiz DG, Jacobson MP, Aggarwal R, Behr SC, Flavell RR, Wilson DM, Seo Y, Evans MJ*. J Nucl Med., 2021, 62 (5), 723-731;

10.  Huang Y, Zhao N, Wang YH, Truillet C, Wei J, Blecha JE, VanBrocklin HF, Seo Y, Sayeed M, Feldman BJ, Aggarwal R, Behr SC, Shao H, Wilson DM, Villanueva-Meyer JE, Gestwicki JE*, Evans MJ*. ACS Chem Biol.202015(6):1381-1391.

9.  Wei Wu, Qiaoling Chen, Yishi Tian, Yihui Xu, Yangjie Huang*, Yi You* and Zhiqiang Weng*, Org. Chem. Front.2020, 7, 1878-1883.

8.  Zheng Fang, Hongshan Yin, Lu Lin, Shunli Wen, Lili Xie*, Yangjie Huang*, and Zhiqiang Weng*, J. Org. Chem.202085, 8714–8722.

7.  Yangjie Huang, Xing He, Xiaoxi Lin, Mingguang Rong, and Zhiqiang Weng*, Org. Lett.201416, 3284-3287.

6.  Yangjie Huang, Xing He, Haohong Li* and Zhiqiang Weng*, Eur. J. Org. Chem.2014, 7324–7328. 

5.  Yangjie Huang, Jianping Ding, Chuyi Wu, Huidong Zheng,* and Zhiqiang Weng*, J. Org. Chem., 201580, 2912-2917.

4.  Yangjie Huang, Ronglu Huang, Zhiqiang Weng*, Synlett201526, 2327-2331

3.  Yangjie Huang, Manjaly J. Ajitha, Kuo-Wei Huang,* Zhongxing Zhang, and Zhiqiang Weng*, Dalton Trans.201645, 8468–8474.

2.  Zhao N, Huang Y, Wang YH, Muir RK, Chen YC, Hooshdaran N, Wei J, Viswanath P, Seo Y, Ruggero D, Renslo AR*, Evans MJ*. J Nucl Med.202162, 949-955.

1.  Ronglu Huang, Yangjie Huang, Xiaoxi Lin, Mingguang Rong, and Zhiqiang Weng*, Angew. Chem. Int. Ed.2015, 54, 5736-5739.