个人简介
姓名:陈美莲
性别:女
职称:助理研究员
主要研究方向:微生物与植物互作的分子机理,真菌效应蛋白的功能研究,微生物脂肪酶的分子改造等。
教育经历:
2006.09 - 2010.06,福建农林大学,植物保护专业,获农学学士学位;
2007.09 - 2010.06,福建农林大学,会计学专业,获管理学第二学士学位;
2011.09 - 2014.06,福建农林大学,植物病理学专业,获农学硕士学位;
2014.09 - 2018.12,福建农林大学,植物病理学专业,获农学博士学位;
(在此期间,2016.10.23-2018.10.16系美国德州农工大学联合培养博士生)。
主要参加科研项目情况
1、国家自然科学基金青年科学基金项目,稻瘟病菌效应蛋白MoHag4的功能及其与水稻靶标OsbZIP39的互作机制研究,32001976,2021-2023,主持
2、福建省自然科学基金青年科学基金项目,新效应蛋白MoHag1调控稻瘟病菌致病机理的研究,2020J05177,2020-2023,主持
3、国家自然科学基金面上项目,极体(Polarisome)复合体在禾谷镰刀菌致病过程中的作用机制研究,31970141,2020-2023,参与
4、国家自然科学基金面上项目,稻瘟病菌转座元件转座活性的表观调控及其与无毒基因功能关系的研究,31770156,2018-2021,参与
5、国家自然科学基金海峡两岸联合基金项目,基于闽台稻瘟病菌群体演化特点探讨水稻持久抗瘟生态防控策略,U1305211,2014-2017,参与
6、国家自然科学基金重大研究计划,无毒基因AvrPiz-t变异过程中稻瘟病菌基因组微进化特点研究,91231121,2013-2015,参与
近五年主要研究成果
1. Anjago WM, Zeng W, Chen Y, Wang Y, Biregeya J, Li Y, Zhang T, Peng M, Cai Y, Shi M, Wang B, Zhang D, Wang Z*, Chen M*. The molecular mechanism underlying pathogenicity inhibition by sanguinarine in Magnaporthe oryzae. Pest Manag Sci. 2021, 77(10):4669-4679.
2. Zhenhui Zhong, Meilian Chen, Lianyu Lin, Ruiqi Chen, Dan Liu, Justice Norvienyeku, Huakun Zheng, Zonghua Wang. Genetic Variation Bias toward Noncoding Regions and Secreted Proteins in the Rice Blast Fungus Magnaporthe oryzae. mSystems. 2020, 5(3):e00346-20.
3. Meilian Chen, Baohua Wang, Guodong Lu, Zhenhui Zhong, Zonghua Wang. Genome Sequence Resource of Magnaporthe oryzae Laboratory Strain 2539. Mol Plant Microbe Interact. 2020, 33(8):1029-1031.
4. Zhenhui Zhong, Lianyu Lin, Huakun Zheng, Jiandong Bao, Meilian Chen, Limei Zhang, Wei Tang, Daniel J Ebbole, Zonghua Wang. Emergence of a hybrid PKS-NRPS secondary metabolite cluster in a clonal population of the rice blast fungus Magnaporthe oryzae. Environ Microbiol. 2020, 22(7):2709-2723.
5. Zhenhui Zhong, Lianyu Lin, Meilian Chen, Lili Lin, Xiaofeng Chen, Yahong Lin, Xi Chen, Zonghua Wang, Justice Norvienyeku, Huakun Zheng. Expression Divergence as an Evolutionary Alternative Mechanism Adopted by Two Rice Subspecies Against Rice Blast Infection. Rice (N Y), 2019, 12(1):12.
6. Zhong Z#, Chen M#, Lin L, Han Y, Bao J, Tang W, Lin L, Lin Y, Somai R, Lu L, Zhang W, Chen J, Hong Y, Chen X, Wang B, Shen WC, Lu G, Norvienyeku J*, Ebbole DJ*, Wang Z*. Population genomic analysis of the rice blast fungus reveals specific events associated with expansion of three main clades. The ISME J., 2018, 12(8):1867-1878.
7. Bao J#,Chen M#, Zhong Z#, Tang W#, Lin L, Zhang X, Jiang H, Zhang D, Miao C, Tang H, Zhang J, Lu G, Ming R, Norvienyeku J*, Wang B*, Wang Z*. PacBio Sequencing Reveals Transposable Elements as a Key Contributor to Genomic Plasticity and Virulence Variation in Magnaporthe oryzae. Molecular Plant, 2017, 10(11):1465-1468.
8. Norvienyeku J#, Zhong Z#, Lin L#, Dang X,Chen M, Lin X, Zhang H, Anjago WM, Lin L, Abdul W, Wang Z*. Methylmalonate-semialdehyde dehydrogenase mediated metabolite homeostasis essentially regulate conidiation, polarized germination and pathogenesis in Magnaporthe oryzae. Environ Microbiol., 2017, 19(10):4256-4277.
9. Khalid Abdelkarim Omer Matar, Xiaofeng Chen, Dongjie Chen, Wilfred Mabeche Anjago, Justice Norvienyeku, Yahong Lin, Meilian Chen, Zonghua Wang, Daniel J. Ebbole, Guodong Lu. WD40 repeat protein MoCreC is essential for carbon repression and is involved in conidiation, growth and pathogenicity of Magnaporthe oryzae. Curr Genet, 2016, DOI: 10.1007/s00294-016-0668-1.
10.Zhenhui Zhong#, Justice Norvienyeku#, Meilian Chen#, Jiandong Bao#, Lianyu Lin, Liqiong Chen, Yahong Lin, Xiaoxian Wu, Zena Cai, Qi Zhang, Xiaoye Lin, Yonghe Hong, Jun Huang, Linghong Xu, Honghong Zhang, Long Chen, Wei Tang, Huakun Zheng, Xiaofeng Chen, Yanli Wang, Bi Lian, Liangsheng Zhang, Haibao Tang, Guodong Lu, Daniel J. Ebbole, Baohua Wang*, Zonghua Wang*. Directional Selection from Host Plants Is a Major Force Driving Host Specificity in Magnaporthe Species. Scientific Reports, 2016, 6:25591 | DOI: 10.1038/srep25591.